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18 April 2008


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I'm so sorry Christie. Fingers crossed for Kyrie. This stuff is scary.


Sympathy and good thoughts for you and Kyrie.

Leslie k

I'm so sorry Christie ! Can the med grade honey be used together with the antibiotics ? Maybe both would work better than 1.


I am so sorry Christie.

IF Kyrie were a person, I'd recommend looking at the book - The Cure is in the Cupboard which is about Oil of Wild Mountain Oregano. I don't know of anyone's experience with Oregano oil and dogs, good or bad. And this is NOT the same as the spice in the cabinet.

I'd not stop vet treatment, but rather tell him and try using both, if you confirm others have tried it successfully with dogs.

It is a very effective natural antibiotic, antifungal, and antiviral. Capsules of it can knock out a sinus infection quicker than normal Rx antibiotics.

I see that medical is again selling a couple items that contain colloidal silver for infection treatment. One is in their burn treatment bandage for humans. Apparently they believe silver can prevent or reduce infections although they can't patent it and make a lot of money.


I wouldn't normally post an unsubstantiated "try this" suggestion but since you are feeling so desperate, I feel like I want to offer something/anything. I have corresponded with one person and read online the accounts of others who seem to feel colloidal silver is beneficial in a variety of cases and I wonder if it couldn't possibly 'cause no harm' to try it? I wish I had something more concrete, based on something besides "I heard on the internets..." Will keep a good thought for you and Kyrie.


Suggestion: search for mrsa oregano dogs

I found:


What about using the medical microstatic product Betadine Povidone/Iodine solution? There is an ointment too. It is used as a surgical scrub, and available over the counter. I'd still ask the dermatologist vet about using it on the wound.

I see the company brochure mentions it as effective with mrsa and mentions safe use with dogs.

L. Shank

Has CS or EO ( have read report that EO have been successful) considered? My heart goes out to both Kyrie and owner. Loo


Christie - I am so sorry. Best of luck and good thoughts to you and Kyrie.


So sorry Christie for you and Kyrie. Once this

is healed, please look into why this infection keeps occurring. The antibotics are only working

on the surface.


Oy! My gosh, I hope she feels better quickly and that this is the last go round. Even if you have to start antibiotics first, a biopsy may still yield valuable info. If there is some underlying process, the antibiotics should not mask that on a microscopic evaluation.

Unfortunately deep set resistant skin infections and cellulitis are occaisionaly an issue for bulldogs coming into rescue. I would add that we treat for an extended period of time. In some cases up to 6 weeks Unpleasant for some dogs who have sensitive stomachs but it is sometimes the only way to get all of the infection.

In general, until there is normal hair growth coming in all over the area, we do not let our guard down.

Does anyone remember STA lotion? It as a staple of large animal medicine when I was involved with horses. Equal parts isopropyl alcohol, tannic acid and salicylic acid. It was a tremendous surface disinfectant, very useful for small wounds to prevent infection in less that pristine conditions. The main draw back was that it stung for a few seconds until the salicylic acid (the basis for aspirin) kicked in.


Christie I am so sorry. I know your despair so well. Let me tell you what we did in a similar situation. My dog had multiple surgeries on his neck and I am going to leave out the LONG details but suffice it to say he contracted a MRSA type bacteria in his neck from the Vets. He was in an unsanitized kennel and I am sure touched without gloves. What he took was a very high dose of Baytril (I gave 5 or 6 136mg a day) plus 300 mg of Clinamycin at the same time. My dog is about 95lbs. He took these for longer than is recommended, about a month if I recall. It worked. He tolerated it well with pill pockets back when pill pockets were good and had the cultures in it before Greenies bought and ruined the product. I also gave him oral cultures for a weeks in the midst of it all that the vet gave me from a tube that I would inject into his mouth and that helped a great deal.

If this didn’t work my vet was going to order some Medi Honey from Europe. This is evidently remarkable and is used in Europe. Our drug makers don’t want this approved here because then their drugs won’t be necessary.

Don’t discount the Baytril. It may be that the dose was not high enough. And yes the bacteria can mutate while on the drug which is why we gave the second drug at the same time. I believe two drugs is protocol for this reason. Talk to your vet aboout that. My vet's father was an old vet who specialized in infectious disease and he consulted with his father. His treatment may be from the old school a bit but all I cared about was that it worked.

Hugs and prayers are sent for your dog’s full and speedy recovery.


CLAY! Darn - I wish I could remember where I read the article or maybe heard it on NPR. Someone is doing testing on various clay's and one of them killed the MRSA. They have to do more testing as to what clays work on what issues but they actually know what clay works on this. I also heard a story awhile back about a hospital testing a particular cleaning product and their instances of MRSA went down as it killed the germs. I will have to see if I can find the sources of this info.


Here is an article on the clay:

Colorado Transplant

Because my cat was diagnosed with herpes in the eye yesterday, along with the antiviral and antibiotic drops, the veterinarian prescribed interfuron and L-lysine to boost the immune system.

I was wondering if giving drugs to boost the immune system--especially interfuron--would help any. Just a thought.

Colorado Transplant

Just want to add how crazy I was getting with my cat's eye sickness.

When you love an animal, it is horrible to see it suffer. especially when there is not a quick fix for a cure.


I am really sorry to hear about Kyrie. I had a friend who had MRSA last fall and she almost died. It was really bad in Cincinnati - I really hope you get rid of it Christie. I'll be thinking good thoughts for her.


Check it out:

Staphylococcus aureus and wounds: A review of tea tree oil as a promising antimicrobial.


AJIC: American Journal of Infection Control. 32(7):402-408, November 2004.

Halcon, Linda PhD, MPH, RN a; Milkus, Kelly BA b


Antibiotic-resistant bacteria continue to be a major health concern worldwide. In particular, Staphylococcus aureus, both methicillin-resistant and -sensitive, are of concern in their ability to cause difficult skin and underlying tissue infections. Melaleuca alternifolia oil (tea tree oil), an essential oil, has demonstrated promising efficacy in treating these infections. Tea tree oil has been used for centuries as a botanical medicine, and has only in recent decades surfaced in the scientific literature as a promising adjunctive wound treatment. Tea tree oil is antimicrobial, anti-inflammatory, and has demonstrated ability to activate monocytes. There are few apparent side effects to using tea tree oil topically in low concentrations, with contact dermatitis being the most common. Tea tree oil has been effective as an adjunctive therapy in treating osteomyelitis and infected chronic wounds in case studies and small clinical trials. There is a need for larger clinical trials to further examine efficacy of tea tree oil as an adjunctive wound therapy, as well as improved guidelines for developing plant-based medicines.


Please have her checked for hypothyroidism. The blood should go to Michigan State University for accurate results. If any of the thyroid values are too low, it's worth trying thyroid supplementation. When my elderly Collie went through a similar MRSA catastrophe, we started him on thyroid supplementation before getting the results back because he was clearly going to die despite antibiotic treatment. The results were miraculous, and the thyroid panel later confirmed that he was hypothyroid. He also turned out to have pancreatic insufficiency, and treating this with pancreatic enzymes has completely resolved some lingering skin/coat problems.

Karen Goodhart

Hi Christie,

I am so sorry to hear about your pooch.

I've never been through this with my pets, but my daughter neearly died seven years ago from a drug-resistant bacteria.

The CDC was involved growing cultures and testing different antibiotics. After 16 days in a Children's ICU and two surgeries, they gave her an antibiotic that had not been used in 12 years.

Because the bacteria and never been exposed to the antibiotic, there was no resistance to it and 5 days later we came home.

It may be the case that your vet should look to the past for a treatment.

Good luck! Ya'll are in my prayers.


No suggestions. Just a lot of sympathy. Hope you find relief for Kyrie soon.


I wanted to mention one further thing that happened while we were dealing with the MRSA. If an abscess has formed somewhere in the body deep in the skin or in an organ, the antibiotic is not going to penetrate the protective walls of the abscess. What could be happening is that there is an abscess somewhere with a fistula tract to the skin surface. So even though you are clearing up the skin, the bacteria hiding in the abscess come out after the antibiotic is finished through the fistula tract toward the skin and the infection returns.

This happened to my dog. He had an abscess form deep in the neck tissue with an extremely thick barrier around it. A microscopic fistula tract was present leading to the skin surface where the infection was visible. This is the bodies way of trying to expel the invader if it can.

The abscess was discovered and it was surgically drained and opened so there was no longer a hiding place. He had to have a drain in his neck after to keep the area open so the drugs could get all the bacteria. Had we not found this, the infection would have returned to the skin surface through the fistula tract after treatment for sure.

Also, he had cultures for both aerobic and anaerobic organisms and sure enough he had both. Anaerobic organisms survive within the body without air so they were having a grand time in the abscess. So you have to check for both. It was the pathologist who discovered the fistula tract because we did a surgical biopsy of the infectious mass that presented at the skin surface.

I am just throwing this out there as something to be considered due to the recurrent nature of the infection. You can check the body and organs with scans, perhaps a sonogram or possibly certain blood tests I am not sure.


I don't know if this will help you and how MRSI in dogs differs from MRSA, my sister recently had MRSA pneumonia and was in the hospital for a week. They gave her IV combination of doxycycline and ceftriaxone after trying virtually every other antibiotic alone and in combination. Though these exact drugs may not be helpful, something else from their class maybe? Also, I know in humans that the approach for multidrug resistant bugs is (eventually) combination therapy. I'm so sorry for you and your dog, I hope it all works out.

Christie Keith

I want to thank everyone for the feedback and sympathy and suggestions on Kyrie. It made me feel all warm inside. :)

We did try essential oils in the beginning, and they had no effect whatsoever. I used a number of herbal remedies, salves, washes, and teas, as I've been studying essential oils and herbal medicine for over 20 years. This thing laughed at everything I tried, which is why I ended up at the vet in the first place. I'd never seen anything like it.

The initial diagnosis was a spider bite, however, when I investigated this, I found that we have no brown recluse spiders in San Francisco, that nearly all MRSI infections in dogs are initially misdiagnosed as a spider bite, and that was actually a highly, highly unlikely cause. Then the culture revealed not one but two strains of drug-resistant staph, one in very large numbers... so I think we can rule that out.

We did test her thyroid and it was a tiny bit low, although her vet said that was probably sick euthyroid syndrome, and I agree. We are going to run the full Michigan panel soon, but the truth is, Kyrie has absolutely zero symptoms of hypothyroidism. I'm not saying she doesn't have it, but there is no sign of it -- she's skinny and active. But we will be checking.

I'm a confirmed colloidal silver skeptic. I've tried it for many things, including my own rashes, over the years, and it's never done diddly for anything. And every time anyone I know mentions that the CS they tried had no effect, we're assured that we were just using the wrong concentration, the wrong brand, we have to make our own, we have to use this kind... I'm sorry. At this point it would take some really compelling scientific evidence to make me reconsider colloidal silver. I honestly think it has, at best, a mild anti-microbial effect, as do many, many other substances that have far more in the way of evidence to support their use.

I have ordered some medical grade honey and intend to try that. I've also been looking into some of the clays. I agree that these bacteria wouldn't be causing symptoms if Kyrie were completely healthy, and yet -- she's 9 years old, never been sick a day in her life, has been on a homemade diet since she was 7 weeks old -- other than the slightly low thyroid reading, all her bloodwork is normal, in fact, her vet said she has the bloodwork of a one-year-old dog. Kidneys in great shape, heart sounds good, liver normal ... no clues that she could have some lurking immune problem or underlying disease.

I'll definitely keep everyone posted and thank you again for all your help!


"We did test her thyroid and it was a tiny bit low, although her vet said that was probably sick euthyroid syndrome, and I agree. We are going to run the full Michigan panel soon, but the truth is, Kyrie has absolutely zero symptoms of hypothyroidism. I’m not saying she doesn’t have it, but there is no sign of it — she’s skinny and active."

My Collie had absolutely no signs of hypothyroidism either--except his inability to fight off the MRSA infection. A brief course of thyroid supplementation will not harm Kyrie even if her thyroid is normal. If I hadn't tried thyroid supplementation with my Collie, his MRSA infection would have killed him.


Christie, I'm really sorry to hear about Kyrie.

Re: hypothyroid; I have had two goldens who tested low normal for thyroid with no hypothyroid type symptoms. They were both showing compromised immune systems at the time - we did a short course of thyroid and both got better. Since then I believe it was Jean Dodds who wrote that there are different breed normals for thyroid

Re: treatment with Baytril

My doctor now uses Zeniquin in place of Baytril. We used it for 8 weeks on a suspected deep dermal infection which later turned out to be something totally different..however while on 8 weeks blood tests remained normal

O3: I think I read somewhere that hospitals are using hyperbaric chambers now for bad cases of MRSA and also hospitals are starting to use "O3" for sterilizing.

Your vet or local hospital might know if "O3" is available for use in animal treatment



Christie, really sorry to hear about your pet.

David Winston is a very well-known herbalist and is speaking on MRSA at an herbal medicine conference in MA soon. He has been writing on the subject. I haven't tried to treat MRSA but two things...slathering honey on the wound is a definite possibility and is non-toxic for your pet. However, doesn't work for internal. I don't know if dogs can handle Oregon grape root tincture. Check with some herbalist vets. But there is some very good work on the synergy of two compounds (one a very weak antimicrobial and the other an inhibitor of the MDR pump) in Oregon grape root. Companies are now working on using this idea from nature for the surfaces of tables and such. See David Winston:


Hi Christie (and everyone)

I'm so sorry to hear about your struggles to cure Kyrie - I know it can be heartbreaking to watch your baby suffer. I have a question for you all since my own dog has been sick off and on for years now and the vets haven't been able to figure out what is going on exactly. Through my research, I've been to make an educated guess that she is at least defficient in zinc, which is apparently common in huskies and whose symptoms matched hers with itchy red skin that can break out all over when she has a crisis outbreak about once a year. Normally, it just stays on her paws and doesn't fully go away. I have a very difficult time to keep her from licking them constantly and hate to subject to her to booties and the collar to stop her all the time, but unfortunately it is the only thing that works. She is currently having one of her outbreaks and is barely eating on her own. I've been reading about wild oregano oil and was wondering if it is something you tried. If so, did it work and how much did you give her...I bought a highly concentrated version of the tincture and I'm hopefull. Any advice anyone is willing to give is more than welcome.

Keep your Courage and Hope alive Christie and all my prayers for you and Kyrie


If you read this, my little rescue beagle has been diagnosed with MRSI and I'm very curious about the med grade honey treatment. I'd appreciate more information! Thank you!!

Christie Keith

Beth, Convenia is a cephalosporin, one of the MOST common drugs to with MRSI is resistant. Furthermore, it persists in the body for months, and at the end, it's at very low, sub-therapeutic levels... which is a RECIPE for creating drug-resistant bugs.

Convenia is a drug of last resort for fractious cats who can't be treated any other way; to use it for MRSI makes no sense to me. The whole POINT of "Convenia" is CONVENIENCE... hence the name. It's certainly not a new antibiotic, and while there are huge benefits to being able to give a single injection instead of daily pills, none of them has anything to do with it being more effective against resistant bugs. Quite the contrary.

Also, you say your vet had your dog on Baytril for two months, but staph becomes resistant to Baytril almost immediately even if it tests out sensitive to it at first; this is widely known. The fact that your vet gave it for two months without finding that out concerns me, and using Convenia for MRSI concerns me, too.

Chloremphenicol is a pretty good drug for MRSI, but the question I have is this: Did the bacteria test out sensitive to it? There's no reason to guess.


Pam, please ask your vet about the new Convenia shot that's just been approved. My sweet pug had it last week (after 2 months of Baytril to which the bacteria became immune) and her sore has dried up and looks like it's healing. The vet also wants to start her on an oral antibiotic called Chloramphenicol in conjunction with the Convenia. But I just read online that the bacteria will also become resistant to the Chloramphenicol. So I am prayin that the Convenia will do it. It stays in the system for 14 days. I'm sure she will need another shot then. I will also look for the med grade honey.

Good luck to you Pam. I feel for you.


Thank you Christie. After more research, I discovered the facts you detailed. And this concerns me too! I am looking for another vet well-versed w/MRSI. The culture did show sensitivity to Chloramphenicol. But I pray the long 2 months on Baytril did no damage.

Do you have any suggestions? I feel so bad for my little one.


Did you see Christie's post on medical grade honey?

It seems to have done the trick for her Kyrie...check it out.

Christie Keith

Yes, I would try medical grade honey along with the Chloro.... and consult a veterinary dermatologist who has seen a lot of MRSI and cleared it successfully. A specialty practice or veterinary college are the best bets for finding someone like that.

Good luck!


I finally found the med grade honey online and ordered a jar. Sweetie's wound has dried up and is healing on the chloramphenicol, but she is quite lethargic with a depressed appetite. Thank you for your suggestions. I do appreciate being able to talk about this.


Will she let you hand feed her?

Sometimes when my animals have been sick, if I feed them something very easy to eat (soft and almost liquid consistency), on my finger, they will take it that way...just to get them started eating again. Hope this helps.


Yes, the hand feeding helps most of the time. Thanks.

Christie Keith

The chloramphenicol can be nasty.... Rebel had a terrible reaction to it, very depressed, weak, lethargic, even stumbling and confused. We had to stop giving it to him. Kyrie, however, tolerated it well.


I remember my animal sciences prof talking about chloramphenicol. I don't remember the exact quote but it was something along the lines of

" Great drug, works wonders. Oh, except for the occasional death"

I've used it, but my vet and I were very very careful with those first few doses.

I have never had to give one of my dogs one of the cutting edge truly big guns, but I am allergic to flagyl. Six years ago my doctor thought I might have been exposed to a parasite that was implicated in a food poisoning outbreak here in Ukiah. The two drugs that worked on it? Flagyl or vancomycin (sp?). IV vancomycin was compounded for me to take orally, was over 80.00 a dose for a three times a day regiment and was the worst tasting substance imaginable. But the pill form was 120.00 a dose! The only good news was after three days my tests all were negative and I could stop taking it but the insurance company would not pay for over a year because of course flagyl would have cost pennies even though it would have killed me.

Christie, I hope you are able to find a solution that is not horridly expensive. If the drug you need comes in different forms, ask if the least expensive form, ie IV solution etc... can be compounded for a lower expense and still be effective.

And most importantly, I hope Rebel is better ASAP.


I am sorry to hear about all of these furry babies going through this struggle. My little 10 year old pom Chester had back surgery in January because he was paralyzed. Died 3 times over 3 days in ICU and had a traccheal stent put in because his collapsed and fought of pnuemonia. After all of this he is walking, yapping, chasing birds and happy. BUT ... the sore on his neck where the IV's went in never healed. To make a long story short 9 months of testing and anti biotics led us to a MRSI result. He has been on Chloramphenicol for 10 days and is lethargic (sleeping 23 hours a day) and confused. I feel like we have won the battle, but are losing the war. He came back strong and now looks like he is dying. I am waiting for his blood work to come back now to see what may be going on. I have spent $12,000 on my baby and the year isn't over. This is a terrible battle we are waging, let's hope we are successful. I don't want to see anymore furry kids suffer. Wish us luck.



I found a website for Pets' Best Rx. I ordered the staph infection combo and it worked wonders. I finished the chloramphenicol while treating my baby with the staph spray and wash. I also washed her bedding every time I gave a bath with the staph wash, which was 3x/week. The spray is awesome. Her hair is finally growing back after 6 months. It is also good for maintenance going forward with any skin infections/rash, etc.

Good luck to you. I know it weighs heavy.


I was searching for info on cats w/MRSI, we just got the diagnosis and are awaiting the call from vet to go forward w/next step, she mentioned possible IV and amakacin? there isn't much to look at on this with cats, she has NO open wounds, was on anit's 4ever and we cultured her urine b/c she was leaking for LONG time off and on(crystals) ?year. Tried Zeniquan and no luck. Been on super low dose of prednisone for years for ear flare ups...any advice as we move forward? pred 4 so long always made me worry. so sorry to hear of your stressful journeys but glad to know there are some great recovery cases too ;p))



Wish I had something to tell you--I understand that the treatment for cats is a little different than dogs (mine is a pug). I think that the pred contributed to my pooch's compromised immune system and set her up to get the MRSI. I've read the feline IV treatment works well. Good luck to you. Just stay diligent and don't be afraid to get a second opinion or even a third.


**thanks for your support, she got better and is now MRSI free, knock on wood.

Christie Keith

Deborah, you have to ask your vet to do a culture and then show you the results from the lab. Don't just let him blow you off. Knowledge is power. You need to KNOW what the bug is. If he's already done a culture, ask him to show you the lab report.

Do you have a vet school or veterinary dermatologist anywhere accessible? You'd likely only have to go once or twice.


Oh, I forgot to mention, that my sister has a sick beagle that has been battling chronic ehrlichia for years. I suggested that she add coconut oil to his diet and green tea to his water.

Coconut oil is used by cancer and aids patients to boost their immune system and green tea has been proven to boost antibiotics making them more powerful.

Good luck, I wish you well.


As soon as I my cat tries the supplements I hope to report back on how they work. In the mean time any suggestions are welcome.


I can understand what you are going through as I am going through something similar with my cat. I hope Kyrie is better!

My cat was operated on for a benign mammary issue, which went fine but seemed to develope an infection later, her wounds re-opened and started leaking puss. Her stomach also had hard bumps. The vet took her in again and drained her. She was again on antibiotics and everything worked well except a week or 2 later the symptoms came back. Since she has been on off antibiotics. The vet here on the island i live on seems to have given up and the other has a reputation for being a butcher...I asked them to do cultures but the vet said they were just the normal bacteria....I am not sure about his professional opinion. At the moment she is on clindrops and seems slightly better. This is her second week and her planned treatment is for 4 weaks. I am also washing her cuts with betadine, twice a day.

She is eating slightly less, but she is also moving less as it's hot, so that may be normal. Her cuts seem slightly better, but some reopen occasionally with clear puss. Her stomach still feels hard and she doesn't like me to touch it.

I purchased some immune supplements for pets from the website "only natural pet".

Can anyone suggest anything else????

This has been going on for months and we are getting desperate. Please if anyone can suggest something...I am all ears.


Thanks for your response Christie!

There are only two vets on the island and one of them has a reputation for being I am left with only one vet.

If not I would of taken her to see someone else but as things stand I am stuck. When I tried to get information about the culture out of him he says it's just the regular bacteria which should be treatable by the antibiotics he has given me. Then he said maybe she has aids, but i remind him she was tested by him and the tests showed she was healthy. So he says it could be cancer, but I doubt this because she was always so healthy up until the operation he said was necessary.(I am not so sure it was necessary because her stomach was hanging for years...and she never had any problems with it.)

I doubt his word concerning the culture because he never got back to me about results even though I called him several times over a 2-3 period...which is long to wait for an infection.

Christie Keith

Thanks, Deborah... I'm so sorry you've had this terrible time with your kitty, and that you can't seem to get decent vet care where you live.

Kyrie is doing well and has had no further problems since starting thyroid supplementation... knock on wood!


Hi Christine,

Just wanted to give you an update on my use of Only Natural Pet products I am using on Rose my cat which are an Immune Strengthener and a liquid drop product called BSST which are used to purify the blood. I mix these into her food. She does seem better, her appetite seems better, her fur became much nicer, and she doesn't hide, so I don't think she is in pain. Her abscess seems to be seeping a bit still but perhaps its a bit less then befor.

She has been on these herbal supplements for about 2 weeks because the antibiotics made her so sick she stopped eating entirely for about 4 days and I had to force her to take water using a dropper. Then later I cooked chicken breast in water and gave her the water, little by little her appetite returned but I was wary of giving her medication again. I figured if she was going to go, better make things as pleasant as possible rather then force more medicine on her. Then later i gave her the herbal medicine and it took her a while to get use to it but she doesn't seem to mind at all now that she has.

I also tried to get her to use the salmon oil which is suppose to be really good for dogs and cats immunce system but she didn't like it and ate very reluctantly. Then one day she threw up so I have stopped giving her any of the oil.

I will try to keep you updated and wish you the best with Kryie.

take care,


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